Protein Data Bank (PDB)

Assalamualaikum...today i'm gonna tell you about protein data bank.
i know what comes first in your mind when you read the title..you must be like.."What is that?", "Oh...there is bank for proteins..","Really?Bank for proteins?"..and those kind of questions pop up in your head,right?(no?err...)..what is this thing actually?..what can i say about PDB is that PDB is a cloud storage to store all the data about proteins..so,let's find out more about this PDB!!

WHAT IS PDB?

 The PDB is a single worlwide repository for 3D structural data of biological molecules. It is an archive of experimentally determined three-dimensional structures of biological macromolecules that serves a global community of researchers, educators, and students. The data contained in the archive include atomic coordinates, bibliographic citations, primary and secondary structure, information, and crystallographic structure factors and NMR experimental data. It also includes proteins, nucleic acids and viruses.

Moreover,the PDB archive is available at no cost to users. The PDB has an international community of users, including biologists (in fields such as structural biology, biochemistry, genetics, pharmacology); other scientists (in fields such as bioinformatics, software developers for data analysis and visualization); students and educators (all levels); media writers, illustrators, textbook authors; and the general public.
to learn more about this PDB things, visit  http://www.rcsb.org/pdb/home/home.do

I did found some of interesting protein structures when i went through the website. Most of us only know about protein superficially. These are the common ones :

Type of proteins	Functions
Enzymes	Reaction catalysis
Muscles	Structural proteins
Antibodies	Defense proteins
Hormones	Regulatory proteins

However, there are more than that. In the website,you can find all the data including structures and information regarding to protein..Here are some of it :
P.S: click on the link provided for further info


1) Amylase

CRYSTAL STRUCTURE OF THERMOACTINOMYCES VULGARIS R-47 

ALPHA-AMYLASE 2 MUTANT F286A  

 http://www.rcsb.org/pdb/explore/explore.do?structureId=1JF5

2) HtrA

HtrA proteases are activated by a conserved mechanism that can be triggered by distinct molecular cues  

http://www.rcsb.org/pdb/explore/explore.do?structureId=3MH4


3) Lexa

LEXA S119A MUTANT 

 http://www.rcsb.org/pdb/explore/explore.do?structureId=1JHH

4) pepsin

REVISED 2.3 ANGSTROMS STRUCTURE OF PORCINE PEPSIN. EVIDENCE FOR A FLEXIBLE SUBDOMAIN   

http://www.rcsb.org/pdb/explore/explore.do?structureId=3PEP


5) Trypsin

STRUCTURAL EFFECTS INDUCED BY REMOVAL OF A DISULFIDE BRIDGE. THE

X-RAY STRUCTURE OF THE C30A(SLASH)C51A MUTANT OF BASIC

PANCREATIC TRYPSIN INHIBITOR AT 1.6 ANGSTROMS 

http://www.rcsb.org/pdb/explore/explore.do?structureId=7PTI

so..what are you waiting for?? explore PDB if you wanna know more about other structures. Currently there are more than 90 000 structures have been deposited @ the PDB.. that's it for today..arios amigos!